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Up for sale a RARE! ONE OF A KIND.." Nobel Prize Laureates" Signed Nobel Information Sheet. This item is signed by the 3 scientists who shared the prize for chemistry in 1988. Signers are; Johann Deisenhofer, Robert Huber and Hartmut Michel.
30, 1943) is a German biochemist who, along with Hartmut Michel and Robert Huber, received the Nobel Prize for Chemistry in
1988 for their determination of the first crystal structure of an integral membrane protein,
a membrane-bound complex of proteins and co-factors that is essential to photosynthesis. Born in Bavaria, Deisenhofer earned his
doctorate from the Technical University of
Munich for research work done at the Max Planck
Institute of Biochemistry in Martinsried, West Germany, in 1974. He conducted research there until 1988,
when he joined the scientific staff of the Howard Hughes Medical
Institute and the faculty of the Department of Biochemistry at The University of Texas Southwestern Medical Center at Dallas. Together
with Michel and Huber, Deisenhofer determined the three-dimensional structure
of a protein complex found
in certain photosynthetic bacteria. This membrane protein complex, called
a photosynthetic reaction
center, was known to play a crucial role in initiating a simple type
of photosynthesis. Between 1982 and 1985, the three scientists used X-ray crystallography to
determine the exact arrangement of the more than 10,000 atoms that make up the
protein complex. Their research increased the general understanding of the
mechanisms of photosynthesis and revealed similarities between the
photosynthetic processes of plants and bacteria. Deisenhofer currently serves on the board of
advisors of Scientists
and Engineers for America, an organization focused on promoting
sound science in American government. In 2003 he was one of 22 Nobel Laureates
who signed the Humanist Manifesto. He
is currently a Professor at the Department of Biophysics at the University
of Texas Southwestern Medical Center.
Robert
Huber (born 20 February
1937) is a German biochemist and Nobel laureate. known for his work crystallizing an intramembrane protein important in photosynthesis and subsequently applying X-ray
crystallography to elucidate the protein's structure. He was born on 20
February 1937 in Munich where his father, Sebastian,
was a bank cashier. He was educated at the Humanistisches Karls-Gymnasium from
1947 to 1956 and then studied chemistry at the Technische Hochschule,
receiving his diploma in 1960. He stayed, and did research into using crystallography to elucidate the structure of organic compounds. In 1971 he became a director at the Max Planck
Institute for Biochemistry where his team developed methods for
the crystallography of proteins. In 1988 he received the Nobel Prize for Chemistry jointly
with Johann Deisenhofer and Hartmut Michel. The trio were recognized for their work in
first crystallizing an intramembrane protein important in photosynthesis
in purple bacteria, and
subsequently applying X-ray crystallography to elucidate the protein's
structure. The information provided the first insight into the structural
bodies that performed the integral function of photosynthesis. This insight
could be translated to understand the more complex analogue of essentially the same as that in chloroplasts of higher plants. In
2006, he took up a post at the Cardiff University to
spearhead the development of Structural Biology at the university on a
part-time basis. Since 2005 he has been doing research at the Center
for medical biotechnology of the University of
Duisburg-Essen. Huber was one of the original editors of the Encyclopedia of Analytical Chemistry
Hartmut Michel (born
18 July 1948) is a German biochemist, who received the 1988 Nobel Prize in Chemistry for
determination of the first crystal structure of an integral membrane protein, a
membrane-bound complex of proteins and co-factors that is essential to photosynthesis. He was born on 18 July 1948 in Ludwigsburg. After compulsory military service, he studied
biochemistry at the University of Tübingen,
working for his final year at Dieter Oesterhelt's laboratory on ATPase activity of halobacteria. Hartmut later worked on the crystallisation
of membrane proteins -
essential for their structure elucidation by X-ray crystallography. He
received the Nobel Prize jointly
with Johann Deisenhofer and Robert Huber in 1988. Together with Michel and Huber,
Deisenhofer determined the three-dimensional structure of a protein complex
found in certain photosynthetic bacteria. This membrane protein complex, called
a photosynthetic reaction
center, was known to play a crucial role in initiating a simple type
of photosynthesis. Between 1982 and 1985, the three scientists used X-ray crystallography to
determine the exact arrangement of the more than 10,000 atoms that make up the
protein complex. Their research increased the general understanding of the
mechanisms of photosynthesis, revealed similarities between the photosynthetic
processes of plants and bacteria and established a methodology for
crystallising membrane proteins. Since
1987 he has been director of the Molecular Membrane Biology department at
the Max Planck
Institute for Biophysics in Frankfurt am Main, Germany, and professor of biochemistry at
the Goethe University
Frankfurt.